Factors Associated with Phyllodes Tumor After Core Needle Breast Biopsy | Dr. Daniel Gould

Dr. Daniel Gould co-authored this research published in the Journal of Surgical Research, examining factors that may help distinguish phyllodes tumors from other fibroepithelial breast lesions following core needle biopsy.

Fibroepithelial lesions of the breast can present a diagnostic challenge because phyllodes tumors and fibroadenomas may share similar characteristics when evaluated using a limited tissue sample. Determining which lesions require surgical removal is therefore an important part of clinical decision-making.

The researchers reviewed patients whose core needle biopsies identified a fibroepithelial neoplasm and evaluated clinical, imaging, and pathological factors associated with a final diagnosis of phyllodes tumor following surgical excision.

The study explored whether characteristics such as patient age, lesion size, imaging findings, and pathological features could help predict which fibroepithelial lesions were more likely to represent phyllodes tumors.

By identifying factors associated with an increased likelihood of phyllodes tumor, the research aimed to support more informed decisions about when surgical excision should be considered after an indeterminate fibroepithelial finding on core biopsy.

The study contributes to the broader understanding of breast tumor diagnosis and surgical management, particularly in cases where initial biopsy findings cannot reliably distinguish between different types of fibroepithelial lesions.